Pediatrics : Head Lice/Scabies
Concerns about emerging resistance and the potential harm of using permethrins
have prompted a search for effective pediculicidal therapies that are
not harmful to children with repeated use. An herbal formulation has
been shown to be effective for head lice.9 Ivermectin can also be compounded
for topical application or as an oral dose titrated for each patient
for the treatment of head lice and scabies.
Clin Exp Dermatol 2002 Jun;27(4):264-7
Treatment of 18 children with scabies or cutaneous larva migrans using
ivermectin.
Del Mar Saez-De-Ocariz M, McKinster CD, Orozco-Covarrubias L, Tamayo-Sanchez
L, Ruiz-Maldonado R.
Department of Dermatology, National Institute of Pediatrics, Mexico City,
Mexico.
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here to access the PubMed abstract of this article.
Trop Med Parasitol 1994 Sep;45(3):253-4
Efficacy of ivermectin for the treatment of head lice (Pediculosis capitis).
Glaziou P, Nyguyen LN, Moulia-Pelat JP, Cartel JL, Martin PM.
Institut Territorial de Recherches Medicales Louis Malarde, Papeete,
Tahiti, French Polynesia.
Twenty six male and female patients aged 5 to 17 years had head lice
infestation confirmed by eggs presence and received treatments with a
single 200 microgram/kg oral dose of. At day 14 after treatment, 20 had
responded to the treatment (77%), and 6 patients (23%) presented with
a complete disappearance of eggs and all clinical symptoms. At day 28,
7 patients appeared clear of infestation (27%), but 4 of the 6 patients
with no eggs at day 14 presented with signs of reinfestation. This study
suggests that ivermectin is a promising treatment of head lice, and a
second dose at day 10 may be appropriate.
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here to access the PubMed abstract of this article.
J Dermatol 2001 Sep;28(9):481-4
Oral ivermectin in scabies patients: a comparison with 1% topical lindane
lotion.
Madan V, Jaskiran K, Gupta U, Gupta DK.
Department of Dermatology, NSCB, Medical College, Jabalpur, MP, India.
Two hundred scabies patients were randomly allocated to receive either
oral ivermectin in a single dose of 200 micrograms/kg body weight, or
1% lindane lotion for topical application overnight. Patients were assessed
after 48 hours, two weeks and four weeks. After a period of four weeks,
82.6% of the patients in the ivermectin group showed marked improvement;
only 44.44% of the patients in the lindane group showed a similar response.
Oral ivermectin is easy to administer as a single oral dose, induces
an early and effective improvement in signs and symptoms, and compliance
is accordingly increased.
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here to access the PubMed abstract of this article.
Isr Med Assoc J. 2002 Oct;4(10):790-3
The in vivo pediculicidal efficacy of a natural remedy.
Mumcuoglu KY, Miller J, Zamir C, Zentner G, Helbin V, Ingber A.
Department of Parasitology, Hebrew University Medical School, Jerusalem,
Israel.
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here to access the PubMed abstract of this article.
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